Guideto Further Reading

Brater D C, Daly W J 2000 Clinical pharmacology in the middle ages: principles that presage the 21st century. Clinical Pharmacology and Therapeutics 67: 447-450

Breckenridge A1995 Science, medicine and clinical pharmacology. British Journal of Clinical Pharmacology 40:1-9 Breckenridge A1999 Clinical pharmacology and drug regulation. British Journal of Clinical Pharmacology 47:11-12 Dollery C T 1996 Clinical pharmocology: future prospects for the discipline. British Journal of Clinical Pharmacology 42:137-141

2 Self-experimentation has always been a feature of clinical pharmacology. A survey of 250 members of the Dutch Society of Clinical Pharmacology evoked 102 respondets of whom 55 had done experiments on themselves (largely for convenience) (van Everdingen et al 1990 Lancet 336:1448). A spectacular example occurred at the 1983 meeting of the American Urological Association at Las Vegas, during a lecture on pharmacologically-induced penile erection, when the lecturer stepped out from behind the lectern to demonstrate personally the efficacy o) the technique (Zorgniotti A W 1990 Lancet 336: 1200)

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