1

TABLE 9.1 Some specific antidotes, indications and modes of action (see Index for a fuller account of individual drugs)

Antidote

Indication

Mode of action

acetylcysteine

paracetamol, chloroform, carbon tetrachloride

Replenishes depleted glutathione stores

atropine

cholinesterase inhibitors, e.g. organophosphorus

Blocks muscarinic cholinoceptors

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