Individual Local Anaesthetics

Amides

Lignocaine (lidocaine) is a first choice drug for surface use as well as for injection, combining efficacy with comparative lack of toxicity; the t'/2 is 1.5 h. It is also useful in cardiac arrhythmias although it is being replaced by amiodarone for this purpose.

Prilocaine is used similarly to lidocaine (t;/2 1.5 h), but it is slightly less toxic. It used to be the preferred drug for intravenous regional anaesthesia but it is

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