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(prb) - produced from pre insulin synthesised by bacteria using recombinant DNA technology; (pyr) - produced from a precursor synthesised by yeast using recombinant DNA technology; (emp) - produced by enzymatic modification of porcine insulin.

Fig. 35.1 Insulin chart. Reproduced with permission of the Monthly Index of Medical Specialities.This chart is subject to change as companies develop their products.

losing the flexible administration of the right amount of soluble (neutral) insulin to cover the meal following the dose. • Mixed insulin zinc suspension is, confusingly, the approved name for proprietary mixtures of crystalline and amorphous zinc suspension. Mixed insulins are not, therefore, the same as biphasic insulins. While the different proprietary formulations in this group do have differing time courses of action (see Fig. 35.1) depending on their (unstated) proportions of amorphous and crystalline suspension, it is not expected that doctors or patients would vary the formulation prescribed.

The important thing is for the doctor to get to know well a range that will serve most patients. (For insulin regimens and injection techniques, see p. 691.)

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