Suramin or pentamidine is effective during
the early stages but not for the later
neurological manifestations for which melarsoprol should be used. Eflornithine is effective for both early and late stages. Expert advice is recommended.
Prolonged (t -3 months) treatment with
benznidazole or nifurtimox may be
Notes on drugs for protozoal infections
Atovaquone is a quinone; it may cause gastrointestinal and mild neurological side effects, and rare hepa-totoxicity and blood dyscrasias.
Benznidazole is a nitroimidazole that may occasionally cause peripheral neuritis but is generally well tolerated, including by infants.
Dehydroemetine inhibits protein synthesis; it may cause pain at the site of injection, weakness and muscular pain, hypotension, precordial pain and cardiac dysrhythmias.
Eflornithine inhibits protozoal DNA synthesis; it may cause anaemia, leucopenia and thrombocytopenia, and seizures.
Iodoquinol may cause abdominal cramps, nausea and diarrhoea. Skin eruptions, pruritus ani and
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...