Is 30 30 60 6090

Infuse slowly, e.g. 30 mg in 250 ml 0.9% saline over I hour. Expect response in 3-5 days.

Infuse slowly, e.g. 30 mg in 250 ml 0.9% saline over I hour. Expect response in 3-5 days.

5 formerly called aminohydroxypropylidenediphosphonate disodium, APD.

• Phosphate i.v. is quickly effective but lowers calcium by precipitating calcium phosphate in bone and soft tissues and inhibiting osteoclastic activity; it should be used only when other methods have failed.

• Trisodium edetate (therapeutically equivalent to disodium edetate) i.v. chelates calcium and the inert complex is excreted by glomerular filtration. Although it is rapidly effective, it causes pain in the limb receiving the infusion and may cause renal damage.

• Dialysis is quick and effective and is likely to be needed in severe cases or with renal failure.

The above measures are temporary only, giving time to tackle the cause.

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