Pivmecillinam (t% 1 h) is an oral agent closely related to the broad spectrum penicillins but with differing antibacterial activity by virtue of having a high affinity for penicillin binding protein. It is active against Gram-negative organisms including P-lactamase-producing Enterobacteriaceae but is inactive against Pseudomonas aeruginosa and its relatives, and against Gram-positive organisms. Pivmecillinam is hydrolysed in vivo to the active form mecillinam (which is poorly absorbed by mouth). It has been used to treat urinary tract infection. Diarrhoea and abdominal pain may occur.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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