Minor Antimicrobials

These are included because they are effective topically without serious risk of allergy, although toxicity or chemical instability limits or precludes their systemic use.

Mupirocin is primarily active against Gram-positive organisms including those commonly associated with skin infections. It is available as an ointment for use, e.g. in folliculitis and impetigo, and to eradicate nasual staphylococci, e.g. in carriers of resistant staphylococci. It is rapidly hydrolysed in the tissues.

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