Digoxin: maximum dose 500 jtg i.v. over 30 min x 2

Doses throughout are based on an adult of average body weight A starting dose of 6 mg adenosine is currently outside the UK licence for this agent.

*Note 1: Theophylline and related compounds block the effect of adenosine. Patients on dipyridamole, carbamazepine, or with denervated hearts have a markedly exaggerated effect which may be hazardous. tNote 2: DC shock is always given under sedation/general anaesthesia. **Note 3: Not to be used in patients receiving beta-blockers.

Fig. 24.2 (continued)

abnormalities of cardiac failure — particularly, the elevated renin and sympathetic activity — can be caused by drugs used for treatment, as well as by the disease. Renal perfusion is not altered early in heart failure, whereas diuretics and vasodilators stimulate renin and noradrenaline production through actions at the juxtaglomerular apparatus in the kidney and on the arterial baroreflex, respectively.

Advanced life support algorithm for the management of cardiac arrest in adults

Cardiac arrest f

Precordial thump if appropriate

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