Pharmacokinetics see page 713 Preparations Of Oestrogens

The dose varies according to whether replacement of physiological deficiencies is being carried out (replacement therapy) or whether pharmacotherapy is being used.

• Ethinylestradiol (t1/, 13 h) is a synthetic agent of first choice for pharmacological (mainly contraceptive) uses; it is effective by mouth.

• Estradiol and estriol are orally active mixed natural oestrogens.

• Conjugated estrogens (Premarin) are orally active mixed natural oestrogens containing 50-65% oestrone obtained from the urine of pregnant mares.5

• Estropipate (piperazine oestrone sulphate) is an orally active synthetic conjugate.

• Stilboestrol (diethylstilbestrol) is the first synthetic oestrogen: its use is confined to androgen dependent cancers (breast, prostate).

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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