Proarrhythmic Drug Effects

All antiarrhythmic drugs can also cause arrhythmia; they should be used with care and ideally only following advice from a specialist. Such proar-rhythmic effects are most commonly seen with drugs that prolong the QT interval or QRS complex of the ECG; hypokalaemia aggravates the danger. Quinidine may cause tachyarrhythmias in an estimated 4-6% of patients. A probable proarrhythmic effect of flecainide resulting in a doubling of mortality was revealed by the Cardiac Arrhythmia Suppression Trial (CAST) (see p. 502).

Digoxin can induce a variety of brady- and tachyarrhythmias (see above).

Was this article helpful?

0 0
Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

Get My Free Ebook

Post a comment