Proarrhythmic Drug Effects

All antiarrhythmic drugs can also cause arrhythmia; they should be used with care and ideally only following advice from a specialist. Such proar-rhythmic effects are most commonly seen with drugs that prolong the QT interval or QRS complex of the ECG; hypokalaemia aggravates the danger. Quinidine may cause tachyarrhythmias in an estimated 4-6% of patients. A probable proarrhythmic effect of flecainide resulting in a doubling of mortality was revealed by the Cardiac Arrhythmia Suppression Trial (CAST) (see p. 502).

Digoxin can induce a variety of brady- and tachyarrhythmias (see above).

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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