Quantitative aspects

That a drug has a desired qualitative action is obviously all-important, but it is not by itself enough. There are also quantitative aspects, i.e. the right amount of action is required and with some drugs the dose has to be very precisely adjusted to deliver this, neither too little nor too much, to escape both inefficacy and toxicity, e.g. digoxin, lithium, gentamicin. Whilst the general correlation between dose and response may evoke no surprise, certain characteristics of the relation are fundamental to the way drugs are used. These are:

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