Synopsis

The range of antibacterial drugs is wide and affords the clinician scope to select with knowledge of the likely or proved pathogen(s) and of factors relevant to the patient, e.g. allergy, renal disease.Antibacterial drugs are here discussed in groups primarily by their site of antibacterial action and secondly by molecular structure, because members of each structural group are usually handled by the body in a similar way and have the same range of adverse effects.

Table 11.1 (p. 211) is a general reference for this chapter.

Lesser categories of P-lactams include

— P-lactamase inhibitors (e.g. clavulanic acid).

Other inhibitors of cell wall synthesis include vancomycin and teicoplanin.

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