Infection is a major category of human disease and skilled management of antimicrobial drugs is of the first importance.The term chemotherapy is used for the drug treatment of parasitic infections in which the parasites (viruses, bacteria, protozoa, fungi, worms) are destroyed or removed without injuring the host.The use of the term to cover all drug or synthetic drug therapy needlessly removes a distinction which is convenient to the clinician and has the sanction of long usage. By convention the term is also used to include therapy of cancer.

• Classification of antimicrobial drugs

• How antimicrobials act

• Principles of optimal antimicrobial therapy

• Use of antimicrobial drugs: choice; combinations; chemoprophylaxis and preemptive suppressive therapy

• Problems with antimicrobial drugs: resistance; opportunistic infection; masking of infections

• Antimicrobial drugs of choice (Reference table)

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