This reaches a peak at 10-11 weeks and usually resolves by 13-14 weeks of gestation. Nausea alone does not require treatment. Much can be achieved by reassurance that the problem is transient and a discussion of diet, e.g. taking food before getting up in the morning. Rarely, a decision is taken to use a drug, and then a histamine 11, receptor antagonist or a phenothiazine, e.g. promethazine (see above) is preferred. Although pyridoxine deficiency has not been shown to complicate simple pregnancy vomiting, it may occur in hyperemesis gravidarum which requires i.v. fluids and multivitamin supplement.
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