Antidiuretic Hormone Syndrome Arginin Vasopressin

The description of hyponatremia, hypervolemia, urinary sodium excretion and high urinary osmolality in 1957, led to the assumption that it was caused by cancer antidiuretic hormone (ADH) production. This syndrome is most commonly associated with oat cell carcinoma of the lung, and about 40% of lung carcinoma patients have increased ADH production [9]. Since only a minority of these patients are symptomatic, it is presumed that the clinical picture also requires increased water intake by the patients.

Table 1. Endocrine/metabolic paraneoplastic syndromes and type of neoplasm (approximate percentage of reported cases)


Ectopic ACTH



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