Conclusion

It seems reasonably clear that combination chemotherapy may be associated with rheumatic manifestations. On the one hand, this may consist of a relatively self-limiting condition characterized by arthralgia and myalgia with negative autoimmune serology and this has been given the name postchemotherapy rheumatism. On the other hand, there may be a rare subgroup of patients who develop an autoimmune connective tissue disease following combination chemotherapy which may represent another facet of the so-called postchemotherapy rheumatism syndrome. In addition, tamoxifen and certain chemotherapy agents such as bleomycin and particularly interferon-« may be associated with the development of diseases such as Raynaud's syndrome, scleroderma or SLE as well as nonspecific rheumatic symptoms such as myalgia and polyarthritis/polyarthralgia. The interaction between these drugs and the immune system and their effects on the balance of self-tolerance may yield useful insights into the pathology of the idiopathic connective tissue diseases.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment