Conclusions

Paraneoplastic vasculitides show a temporal association with onset of the tumor or occur concomitantly with relapse of the tumor. The most common malignancies reported to be associated with paraneoplastic vasculitides are hematologic neoplasms. Cutaneous vasculitides tend to be the most common vasculitic syndromes associated with malignancies. It is impor tant to distinguish paraneoplastic vasculitides from vasculitides masquerading as malignancy and from malignancies mimicking vasculitis. For this purpose objective histological confirmation of the diagnosis of vasculitis is indispensable. On the other hand, a cutaneous vasculitis can be the initial manifestation of malignancy, especially in elderly patients. It is therefore advisable to closely examine elderly patients with cutaneous vasculitis to exclude a concurrent neoplasm. Finally, it is sometimes difficult to distinguish anticancer-therapy-induced vasculitides from malignancy-induced forms of vasculitis.

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