Functional Hallmarks Of Dendritic Cells

Dendritic cells (DC) were first described in 1868 as Langerhans cells in the skin. Steinman and Cohn identified mouse spleen DC in 1973 and defined their morphology, tissue distribution and function by a number of in vitro and in vivo experiments [1-3]. It is now accepted, that DC represent a population of 'professional' antigen presenting cells (APC) with an extraordinary capacity to initiate primary immune responses [4-6], They are the main players in the activation of MHC-restricted T cells, the induction of transplant rejection, and the formation of T-dependent antibodies. On the other hand, DC are pivotal in the induction of central tolerance by deletion of self-reactive thymocytes, and, they can be involved in anergizing mature T cells leading to peripheral tolerance.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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