Hsp 65

Hu 160, Hu 166

Human herpes virus-6 59

Human neurotropic virus 297

Human papilloma virus (HPV) 36, 265, 268, 269, 355, 399

Human T-cell leukemia virus (HTLV) type 1 36, 183, 187, 194

Hurler's syndrome 411

Hydroxiclorochine 432

Hydroxyurea 87

Hypercalcemia syndrome 122

Hypernephroma 141

Hyperphosphaturia 123

Hyper-reninemic syndrome 123

Hyperthyroidism 280, 288, 410, 413

Hypertrichosis lanugiosa acquisita 126

Hypertrophic osteoarthropathy 125, 134, 136

Hypo-y-globulinemia 262

Hypoglycemia syndrome 122

Hypophosphatemia 123

Hypothyroidism 280, 288, 312, 401, 413

ICAM-1 312, 347, 353 IDDM4

Idiopathic thrombocytopenic purpura (ITP) 5, 141, 236, 413

Idiotypic system 2

IFNs 345

IgA 182, 194, 261,264-271 IgA autoantibodies 267 IgA deficient 262 IgA dermatosis 271 IgA nephropathy 121 IgG2-IgG4 deficiency 262 IgM«: 56 IgMk 62, 68

IgMk monoclonal component 61 IL-1 2, 61, 127, 133, 280, 309, 353 IL-1/3 136, 280, 281

IL-2 2, 7, 61, 65, 71, 99, 137, 286, 310, 400, 429 IL-2r94 IL-3 61

IL-4 2, 61, 262, 267, 286, 354, 357, 429 IL-5 262, 354

IL-6 2, 61, 94, 127, 133, 262, 309 IL-7 2, 356 IL-8 280, 309

IL-10 2,61,262, 267,286, 354 IL-12 262, 340, 354, 356, 401 IL-13 61

Immune complex (CIC) 12, 66, 142, 265 Immune thrombocytopenia 413 Immune thrombocytopenic purpura 281 Immunization 402 Immunodeficiency disease 262 Immunologic homunculus 6 Immunosuppression 430 Immunosuppressive 46 Immunosuppressive agents 35 Immunosuppressive therapy 34

Immunotherapy 379, 381, 386, 389, 397, 398, 401, 402, 410

Inclusion body myositis (IBM) 85

Inflammatory bowel disease (IBD) 184

Inflammatory myopathy 287, 424

Insulin dependent diabetes 5

Insulin-dependent diabetes mellitus (IDDM) 105

Insulinitis 402

Insulin-like growth factor (IGF) II 122 Insulin-like growth factor I 312 Insulin-like growth factor-1 (IGF-1) 278 Insulin-like growth factors (IGF-I) 346 Integrin 106, 108 Interferon 35, 285, 425 Interferon-or 87, 426 «-interferon 93, 99, 287

Interferon-y (IFN-j/) 267, 280, 317-321, 326-328, 356

Interleukin (IL)-10 60

Interleukin-(IL)- la 278

Interleukin-(IL)-1 ra 133

Interleukin-(IL)-2 immunotherapy 401

Interleukin-(IL)-2 receptor (IL-2R) 209

Interleukin-(IL)-6 254

Interleukin-2 87, 99

Interstitial cystitis 175

Interstitial lung disease 287

Intestinal lymphoma 264

Intestinal vasculitis 287

Intracellular adhesion molecules 1 (ICAM-1) 311 Intrahepatic chemotherapy 52

Intravenous immune globulin (IVIG) 235, 236, 280, 370-372 Intravenous immunoglobulins 432 y-Irradiation 339, 340 Ischemic colitis 52

Jaccoud's 135 Jchain'T' chain 261 JCV 297-300, 302 Jerne's network theory 386 Jo-1 5 Jun 278

Kaposi's sarcoma 290 Kawasaki disease 52 Keratinocytes 182 Kidney 95

Kikushi syndrome 33 Kinetochore 176

Lambert-Eaton myasthenic syndrome (LEMS) 87, 129, 130

Lamina propria 105

Laminin 106

Langerhans cells 353

Laryngeal carcinoma 265, 312

Latent membrane protein (LMP) 1 399

Latent membrane protein 1 (LMP-1) 27

Leiomyosarcomas 108, 122

Leucocytoclastic vasculitis 425

Leukaemia 20, 23, 31, 34,46, 82, 96, 125, 135, 136, 141, 143, 195,

196, 366, 399,410, 423, 431 Leukaemic arthritis 135 Leukocytoclastic vasculitides 50 Leukocytoclastic vasculitis 49, 287 Leukocytosis 127 Lewis lung carcinoma 400 LFA-353

LH-RH analogues 87 Li-Fraumeni syndrome 170, 181 Lipopolysacharide (LPS) 309-311 Livedo reticularis 287 Liver cancer 179 Liver cirrhosis 59, 135, 165, 195 Liver disease 175 Liver metastases 186, 187

Liver-kidney microsomal antibodies (anti-LKM) 286 1-mycL-myc 160, 161

Long acting thyroid stimulating (LATS) 11 lpr 281 LPS 262

Lung cancer 19, 24, 34, 41, 42, 50, 116, 145, 161, 162, 164, 169,

179, 181, 182, 184-187, 194-197, 267, 268, 312, 431 Lung carcinoma 135, 309 Lupus anticoagulant (LA) 94 Lyl+ B 227 Lyb-1 B 37

Lymph-node hyperplasia 253 Lymphoblastic leukemia 234 Lymphoblastic lymphomas 234 Lymphoblastoid hamartoma 253 Lymphocytic lymphoma 61, 97 Lymphoid follicles/MALT 59

Lymphoma 20, 26, 32, 35, 37, 41, 46, 55, 57, 62, 70-72, 96, 105, 107, 108, 126, 136, 141, 143, 161, 207, 234, 237, 242, 262, 271,423,425,431 Lymphoplasmacytic lymphoma 98 Lymphoproliferation 63 Lymphoproliferative cancer 20, 22, 23 Lymphoproliferative disease 49, 55, 262 Lymphoproliferative disorders 262 Lymphoproliferative neoplasm, 116 Lymphoproliferative tumors 19

Macroglobulinemia 55, 263 Macrophage myofasciitis 85 MAGE 166, 175, 355, 398, 400, 402 MAGE-1 160, 165 MAGE-3 160 Malabsorption 105 Malaria 61

Malignant B-lymphoproliferative disorders 234

Malignant lymphoma 49, 87, 233

Maltoma 237, 238

MALTomas 290

Mamma carcinoma 196, 198

Mammary tumors 268

Mantle cell lymphoma 58

Marginal zone B-cell lymphoma (MZL) 63

Mastocytoma 402

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