Info

a Miners without cancer and symptoms of possible CTD development.

bAge and gender related control group for miners with cancer: men from the same geographical region older than 55 years, no cancer, no CTD symptoms and no environmental exposure to carcinogeneous substances.

a Miners without cancer and symptoms of possible CTD development.

bAge and gender related control group for miners with cancer: men from the same geographical region older than 55 years, no cancer, no CTD symptoms and no environmental exposure to carcinogeneous substances.

(1)311 miners without tumor, but with a possible CTD development: symptoms of a possible development of SSc (Raynaud, diffuse lung fibrosis) or symptoms of possible development of other CTD, esp. SLE: one of the clinical ACR criteria for SLE and/or two or more "minor" signs of possible CTD development [82, 83];

(2) 1304 "healthy" miners regarding cancer and CTD symptoms; and

(3)200 healthy men older than 55 years, from the same geographical region as the miners, but without any environmental exposure to carcinogeneous substances (=age and gender related control group of miners with cancer).

The results are shown in Table 7. The prevalence of CTD typical AAb in miners with tumors or probable tumors is significantly higher compared to healthy miners (p < 0.03) and to a gender and age related control group (p < 0.0002), even if the tumor patients have no CTD symptoms. Particularly anti-topoisomerase I (ATA) and anticentromere antibodies (ACA) may be associated with tumor development.

The higher prevalence of tumors and p53 AAb in miners with CTD compared to those without CTD, the higher prevalence of CTD AAb in miners with cancer regardless of CTD symptoms and the development of cancer in patients with CTD AAb but without CTD symptoms suggest that CTD antibody positive miners should not only be followed-up for the development of CTD, but also for the manifestation of tumors, especially for lung cancer.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment