Peripheral TCell Lymphoma PTCL

This term includes heterogenous diseases such an-gioimmunoblastic T-cell lymphoma, angiocentric lymphoma, intestinal T-cell lymphoma and adult T-cell lymphoma/leukaemia. The majority however are grouped in a category termed "peripheral T-cell lymphoma, unspecified". These latter lymphomas usually affect adults with generalised disease and may involve extranodal sites. The clinical course is often aggressive with frequent relapses [85, 86],

A 65-year-old man with a history of hypertension and ischaemic stroke and recurrent deep vein thrombosis was documented by Onida et al. [87]. Lymph node biopsy was consistent with a diagnosis of PTCL. He had partial obliteration of the main branches of the pulmonary artery and a possible left renal infarct. Multiple diffuse ischaemic lesions were evident on CT brain scanning. He demonstrated elevated IgM aCL of 22 units/ml and a positive lupus anticoagulant test.

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