Summary

Since the discovery of HCV, interest in extrahepatic manifestations which may accompany chronic infection with this virus, is gaining momentum. Of the various systemic manifestations, autoimmune disorders are the most frequently reported and investigated. Recently, epidemiological data indicating an association between chronic hepatitis C, hepatic and extrahepatic malignancies is emerging. The exact underlying mechanism for HCV related oncogenesis is far from being completely understood. HCV has no direct oncogenic effect. Indirect mechanisms such as modulation of autoimmune mechanisms and regulation of oncogenes are probably involved in this process. Theses mechanisms should be better investigated and defined. Moreover, investigation of therapeutic modalities such as antiviral and immuno-modulatory drugs and their role in treatment and prevention of various manifestations of chronic HCV infection is an exciting task.

10 Ways To Fight Off Cancer

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