Summary

This discussion focuses on the implications of recent findings on natural tolerance for the immunotherapy of cancer. It is argued that cancer cells, just like all other cells in the body, are tolerized by active, dominant mechanisms mediated by tissue-specific regulatory T cells which "suppress" inflammatory or otherwise aggressive responses to the antigens they express, even if these are "cancer-specific". It follows that successful immunotherapy of cancer should require prior inacti-vation of such tolerance mechanisms and cells. Based on the limited knowledge concerning the immunobi-ology of regulatory T cells, strategies are proposed to achieve that goal, while calling the attention to the possibility that indiscriminate primings with cancer cells may well result in re-inforcement of dominant tolerance mechanisms and cancer progression.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment