Breast Up Serum Mail

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48. Kandl H, Seymour L, Bezwoda WR. Soluble c-erbB-2 fragment in serum correlates with disease stage and predicts for shortened survival in patients with early-stage and advanced breast cancer. Br J Cancer 1994;70:739-742.

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51. Klein B, Levin I, Kfir B, et al. Soluble c-erbB-2 (P185) in breast cancer patients in relation to prognosis. Oncol Rep 1995;2:759-761.

52. Krainer M, Brodowicz T, Zeillinger R, et al. Tissue expression and serum levels of HER-2/neu in patients with breast cancer. Oncology 1997;54:475-481.

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54. Lipton A, Ali SM, Leitzel K, et al. Elevated serum HER-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol 2002;20:1467-1472.

55. Lipton A, Ali SM, Leitzel K, Demers L, Harvey HA, Chaudri-Ross HA, Brady C, Wyld P, Carney W. Serum HER-2/neu and response to the aromatase inhibitor letrozole versus tamoxifen. J Clin Oncol 2003;21:1967-1972.

56. Lueftner D, Schnabel S, Possinger K. c-erbB-2 in serum of patients receiving fractionated paclitaxel chemotherapy. Int J Biol Markers 1999;14:55-59.

57. Molina R, Jo J, Filella X, Zanon G, et al. C-erbB-2 oncoprotein in the sera and tissue of patients with breast cancer. Utility in prognosis. Anticancer Res 1996;16:2295-2300.

58. Molina R, Jo J, Zanon G, et al. Utility of c-erbB-2 in tissue and serum in the early diagnosis of recurrence in breast cancer patients: comparison with carcino-embryonic antigen and CA 15.3. Br J Cancer 1996;74:1126-1131.

59. Molina R, Jo J, Filella X, Bruix J, Castells A, Hague M, Ballesta AM. Serum levels of c-erbB-2 (HER-2/neu) in patients with malignant and non-malignant diseases. Tumor Biol 1997;18:188-196.

60. Molina R, Jo J, Filella X, et al. C-erbB-2, CEA and CA 15.3 serum levels in the early diagnosis of recurrence in breast cancer patients. Anticancer Res 1999;19: 2551-2556.

61. Narita T, Funahashi H, Satoh Y, Takagi H. C-erbB-2 protein in the sera of breast cancer patients. Breast Cancer Res Treat 1992;24:97-102.

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63. Revillion F, Hebbar M, Bonneterre J, Peyrat JP. Plasma c-erbB2 concentrations in relation to chemotherapy in breast cancer patients. Eur J Cancer 1996;32A: 231-234.

64. Schoendorf T, Hoopmann M, Warm M, et al. Serologic concentrations of HER-2/neu in breast cancer patients with visceral metastases receiving trastuzumab therapy predict the clinical course. Clin Chem 2002;48:1360-1362.

65. Schwartz MK, Smith C, Schwartz DC, Dnistrian A, Neiman I. Monitoring therapy by serum HER-2/neu. Int J Biol Markers 2000;15:324-329.

66. Streckfus C, Bigler L, Dellinger T, Dali X, Kingman A, Thigpen JT. The presence of soluble c-erbB-2 in saliva and serum among women with breast carcinoma: a preliminary study. Clin Cancer Res 2000;6:2363-2370.

67. Sugano K, Kawai T, Ishii M, et al. Clinical evaluation of serum ErbB-2 protein using enzyme immunoassay (ErbB-2 EIA [Nichirei] Gan To Kagaku Ryoho 1994;21:1255-1262.

68. Sugano K, Ushiama M, Fukutomi T, Tsuda H, Kitoh T, Ohkura H. Combined measurement of the c-erbB-2 protein in breast carcinoma tissues and sera is useful as a sensitive tumor marker for monitoring tumor relapse. Int J Cancer 2000;89: 329-333.

69. Visco V, Bei R, Moriconi E, Gianni W, Kraus MH, Muraro R. ErbB2 immune response in breast cancer patients with soluble receptor ectodomain. Am J Pathol 2000;156:1417-1424.

70. Wu JT, Astill ME, Zhang P. Detection of the extracellular domain of c-erbB-2 oncoprotein in sera from patients with various carcinomas: correlation with tumor markers. J Clin Lab Anal 1993;7:31-40.

71. Wu JT, Astill ME, Gagon SD, Bryson L. Measurement of c-erbB-2 proteins in sera from patients with carcinomas and in breast tumor tissue cytosols: correlation with serum tumor markers and membrane-bound oncoprotein. J Clin Lab Anal 1995;9:151-165.

72. Wu Y, Khan H, Chillar R, Vadgama J. Prognostic value of plasma HER-2/neu in African American and Hispanic women with breast cancer. Int J Oncol 1999;14: 1021-1037.

73. Yamauchi H, O'Neill A, Gelman R, et al. Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein. J Clin Oncol 1997;15:2518-2525.

74. Payne RC, Allard JW, Anderson-Mauser L, Humphreys JD, Tenney DY, Morris DL. Automated assay for HER-2/neu in serum. Clin Chem 2000;46:2:175-182.

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76. Leitzel K, Teramoto Y, Konrad K, et al. Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer. J Clin Oncol 1995;13:1129-1135.

77. Hait WN. The prognostic and predictive values of ECD-HER-2. Clin Cancer Res 2001;7:2601-2604.

78. Pegram MD, Finn RS, Arzoo K. The effect of c-erbB-2 Her-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 1997;15:537-547.

79. Gusterson BA, Gelber RD, Goldhirsch A, et al. Prognostic importance of c-erbB-2 expression in breast cancer. J Clin Oncol 1992;10:1049-1056.

80. Muss HB, Thor AD, Berry DA, et al. c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 1994;330:1260-1266.

81. Tsai CM, Yu D, Chang KT, et al. Enhanced chemoresistance by elevations of the levels of p185 neu in the HER-2/neu-transfected human lung cancer cells. J Natl Cancer Inst 1995;87:682-684.

82. Tsai CM, Chang KT, Wu LH, Chen JY, Gazdar AF, Mitsudomi T, Correlations between intrinsic chemoresistance and HER-2/neu gene expression, p53 gene mutations, and cell proliferation characteristics in non-small cell lung cancer cell lines. Cancer Res 1996;56:206-209.

83. Mehta RR, McDermott JH, Heiken TJ, et al. Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy. J Clin Oncol 1998;16:2409-2416.

84. Yu D, Jing T, Liu B. Overexpression of Erb2 blocks taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34 Cdc2 kinase. Mol Cell 1998;2: 581-591.

85. Pegram M, Hsu S, Lewis G. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 1999;18:2241-2251.

86. Esteva FJ, Valero V, Booser D, et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:1800-1808.

87. Hoopmann M, Neumann R, Tanasale T, Schoendorf, T. HER-2/neu determination in blood plasma of patients with HER-2/neu overexpressing metastasized breast cancer: A Longitudinal Study. Anticancer Res 2003;23:1031-1034.

88. Mansour OA, Zekri AR, Harvey J, Teramoto Y, Elahmady O. Tissue and serum c-erbB-2 and tissue EGFR in breast carcinoma: three years follow-up. Anticancer Res 1997;17:3101-3106.

89. Carney, WP. The emerging role of monitoring serum HER-2/neu oncoprotein levels in women with metastatic breast cancer. Lab Med 2003;34:58-64.

90. Eskelinen M, Kataja V, Hamalainen E, Kosma VM, Penttila I, Alhava E. Serum tumor markers CEA, AFP, CA15-3, TPS and neu in diagnosis of breast cancer. Anticancer Res 1997;17:231-234.

91. Joensuu H, Isola J, Lundin M, et al. Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study. Clin Can Res 2003;9:923-930.

92. Pegram MD, Lipton A, Hayes DF, et al. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185 HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 1998;16:2659-2671.

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A Disquistion On The Evils Of Using Tobacco

A Disquistion On The Evils Of Using Tobacco

Among the evils which a vitiated appetite has fastened upon mankind, those that arise from the use of Tobacco hold a prominent place, and call loudly for reform. We pity the poor Chinese, who stupifies body and mind with opium, and the wretched Hindoo, who is under a similar slavery to his favorite plant, the Betel but we present the humiliating spectacle of an enlightened and christian nation, wasting annually more than twenty-five millions of dollars, and destroying the health and the lives of thousands, by a practice not at all less degrading than that of the Chinese or Hindoo.

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