Review Of Published Prognostic Models In Breast Cancer Methodology

Papers were sought that presented new prognostic models for patients with operable breast cancer, or which evaluated a previously published model (validation study), or both of these. Medline®, Embase®, CancerLit®, and other databases were searched late in 2001 (2). Some additional articles were identified after the main searches.

Of the 78 identified articles 17 were excluded as ineligible. The findings that follow are thus based on analysis of data from 61 studies published between 1982 and 2001: 54 presented one or more new prognostic models and 19 included model validation. Table 1 gives characteristics of the studies and the included patients, and Table 2 shows methodological details. Full details of the findings are available elsewhere (2).

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