For their broad utilization, markers need to be implemented into current risk classification systems, such as the tumor-node-metastasis (TNM) classification. Although the decision upon implementation appears to be pending since 1990s, when DTC were mentioned for the first time in the TNM Supplement (33,34), a useful proposal for an appropriate TNM terminology has recently been made by the International Union Against Cancer (UICC) (35). The most recent TNM classification for breast cancer (36) does not qualify the presence of single cancer cells in peripheral blood or bone marrow as metastasis (stage M0), but it optionally reports the presence of such cells together with their detection method [e.g., M0(i+) or (mol+)].

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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