The Influence Of Advanced Age On Cancer Occurrence And Growth

William B. Ershler

Institute for Advanced Studies in Aging & Geriatric Medicine, Washington, DC.

Recently there has been an increased awareness of the overlapping biologic pathways operant in the processes of aging and carcinogenesis. Coincidently, there has been increased interest in both basic and clinical research pertaining to cancer and aging. There remain many unanswered questions about cancer management in geriatric patients, in part, due to the lack of understanding of the influence of age on tumor biology. This review will attempt to establish a framework around themes in aging biology that are relevant to the development and progression of cancer.

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