Cancers Develop from a Single Bad Cell

Cancer cells within a tumor are like any other living community in that they are subject to the same laws of natural selection. Most cancer cells die spontaneously because their genome has been so badly corrupted that they are incapable of maintaining basic housekeeping functions. Of those that survive, one may have a genetic profile that favors rapid growth, so much so that it quickly becomes the only cell type within the tumor. This scenario has been confirmed experimentally by examining characteristics of cancer cells isolated from different regions of a single individual's body. For example, certain forms of leukemia are associated with the presence of the Philadelphia chromosome, created by a translocation between the long arms of chromosomes 9 and 22 (described in chapter 2). Detailed sequence analysis of the DNA spanning the break site shows it is identical in all leukemic cells from a single patient, confirming a common ancestry. In other words, the leukemia cells in that particular patient are all derived from a single cancerous founder cell.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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