Model of the Fertilization Calcium Wave

Fertilization Model

When mature Xenopus laevis oocytes eggs are loaded with an indicator dye e.g., Ca2 -green dextran and stimulated by the fusion of sperm, a propagating wave of intracellular Ca2 release can be observed by backcalculating the free Ca2 concentration Ca2 i x, t from a time-dependent fluorescence signal F x,t according to 8.3 or 8.5 . This fertilization Ca2 wave is an important step in early development. It triggers Figure 8.2 Schematic diagram of the fertilization Ca2 wave model. Ca2 enters the...