Acute and lymphomatous ATL

Results of nonmyeloablative stem cell transplantation have been reported for eight patients wih ATL (five acute and three lymphoma) (Table 63.4).70'71'74'75 Median age was 55 years (range 52-59 years); 50% of patients had either refractory or progressive disease at the time of transplantation, and 25% had a PR. A fludarabine-based regimen was used in all but two cases.70 74 Five out of six patients achieved a CR after transplant; however, median survival was only 2.3 months (range 0.8-9+ months). The two patients who had achieved a CR at the time of transplant were still alive at 8+ and 9+

Table 63.4 Nonmyeloablative allogeneic stem cell transplant for treatment of ATL

Age

Disease

Median

Donor/

Response

Disease

Overall

Cause

Reference

(years)

status

F/U

status

to SCT

controla

survivala

of death

0 0

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