Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic stem cell transplantation using cells collected from an allogeneic donor (allo SCT) is an option being used with increased frequency. In the past, this approach was used less often in view of limited donor availability, and high nonrelapse mortality, in part, due to GvHD. Allo SCT has the potential for improving patient outcome, as there is no infusion of lymphoma cells (normal donor) and the donor effector cells provide the potential for a GvL effect12 (Table 65.1).

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