Autologous Stem Cell Transplant In

Autologous stem cell transplantation has the advantage of use in (1) older patients, (2) those without an HLA match, and (3) those who would not tolerate an allogeneic transplant. A multicenter, pilot, study of 21 MMM patients who received an autologous stem cell (mobilized with granulocyte colony-stimulating factor) transplant25 was recently published with several interesting findings. The procedure was overall surprisingly well tolerated (transplant-related mortality 3/21; 1< day 100), with improvements seen in both cytope-nias and myeloproliferative symptoms.

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