Cd99 Cd34

CD7 CD79a

CD5 CD19

sCD3-

cCD3+

also characterize different stages in thymocyte maturation which, according to recent microarray studies, may identify specific molecular subtypes of lym-phoblastic disease.18 As an example, samples with gene expression profiles associated with TAL1 or LYL1 expression are similar to late cortical thymocytes, have relatively high expression of bcl-2, and demonstrate higher levels of drug resistance and a poorer prognosis.

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