Chronic and smouldering ATL

The use of myeloablative matched-related donor (MRD) allogeneic stem cell transplantation has been reported in only four patients with chronic ATL (Table 63.3).60'67'71 Median age was 40.5 years (range 33-55 years); three patients had a PR and one relapsed disease at the time of transplant. Seventy-five percent of donors were HTLV-1 seronegative. All patients achieved either a CR (75%) or a PR (25%) after transplantation.

Table 63

3 Myeloablative allogeneic stem cell transplant for treatment of ATL

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