Chronic Idiopathic Mf

Chronic idiopathic MF or MF with myeloid metaplasia is a rare condition in which myeloproliferation is associated with increased fibroblast proliferation neoan-giogenesis and extramedullary hemopoiesis. MF may occur in later phases of the other MPDs namely ET, PV, and CML and this reflects the continuum and substantial overlap of clinical features in the MPDs, and given the prevalence of V617F JAK2 mutation adds weight to the need to reconsideration of disease classification as discussed later.

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