Clinical Features In

Patients usually present with symptoms secondary to cytopenias, as the leukemia suppresses normal hematopoiesis. Patients may have pallor, fatigue, and shortness of breath secondary to anemia; bleeding, bruising, and ecchymoses secondary to thrombocy-topenia/coagulation defects; and infections secondary to neutropenia.3 Fifteen to twenty percent of patients will present with fevers, which can result from infection or from the leukemia itself.4 Fewer than 20% of patients will have bone pain.4

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