Clinical Features

PCL is uncommon. Most reports consist of single cases or small series, with the exception of three reviews reporting at least 25 cases each. The main clinical and laboratory features, the response to therapy, and the duration of survival of patients with primary PCL in the three reviews are summarized in Table 84.3. Noel and Kyle27 included patients with PCL diagnosed between 1960 and 1985, while another two series28'40 included patients with a more recent diagnosis of PCL.

Table 84.3 Primary plasma cell leukemia: clinical and laboratory features in three series including at least 25 patients each

Feature Noel and Kyle27 Dimopoulos et al.40 Garcia-Sanz et al.28

Table 84.3 Primary plasma cell leukemia: clinical and laboratory features in three series including at least 25 patients each

Feature Noel and Kyle27 Dimopoulos et al.40 Garcia-Sanz et al.28

No. of patients

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