Combining Independent Prognostic Factors To Predict Outcome

A combination of independent prognostic factors provides greater prognostic information than any one prognostic factor alone. Table 86.5 provides two other models in which readily available prognostic factors have been combined to provide powerful prognostic information.

able 86.5 Combining major prognostic factors to predict outcome in myeloma


Prognostic factors


No. of patients

Overall survival (OS)

Event-free survival (EFS)

Facon et al.73

Deletion 13 by FISH ß2-microglobulin

None high

One high Both high

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