Conclusion

Functional imaging modalities have become valuable tools in the care of lymphoma patients. While Ga-67 scanning provided early benefits, the improved technical ease and greater accuracy of FDG-PET render Ga-67 scintigraphy less relevant in situations in which FDG-PET is available. FDG-PET provides important information in both initial staging of lymphoma and restaging following treatment, but its contribution appears to be dependent on tumor histology and location. Care must be taken in analysis of FDG-PET images, with the clinical scenario and characteristics of uptake guiding interpretation. Currently, FDG-PET should play a complementary role with other studies such as anatomic imaging, with biopsy and pathological confirmation of questionable lesions performed when possible. In the future, FDG-PET will provide increasingly more guidance in evaluation of prognosis and treatment effectiveness.

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