Conditioning Regimens For Hematopoietic Stem Cell Transplantation

As described previously, prior to the infusion of hematopoietic stem cells, patients receive regimens with the intent of "conditioning" or "preparing" the patient for the infusion of hematopoietic stem cells.1,3 Most conditioning or preparative regimens consist of chemotherapy alone or combined with radiation, radioimmunoconjugates, and/or monoclonal antibodies that target T cells (e.g., alemtuzumab).1'3'79'80 The choice of conditioning regimen is dependent upon the type of transplant (allogeneic vs autologous vs syn-geneic) and the specific disease being treated.

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