Definition Of Fever And Neutropenia

A commonly accepted definition of fever, used in the IDSA guidelines, is a single oral temperature of 38.3 °C (101 °F) or more, or a temperature of >38.0 °C

(100.4 °F) for >1 h. The route of temperature measurement is important. Although rectal temperatures are more accurate than oral or axillary temperatures, rectal temperatures are usually contraindicated in the neutropenic patient due to the risk of promoting bacteremia from colorectal organisms.

The definition of neutropenia used in the IDSA Guidelines is an absolute neutrophil count (ANC) of <500 cells/mm3, or a count of <1000 cells/mm3 if a decrease to <500 cells/mm3 is expected.

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