CML is the most common of the CMPDs. It accounts for about 15-20% of all cases of adult leukemias, but less than 5% of all childhood leukemias. It is slightly more common in males than in females and occurs exceedingly rarely during the first decade of life. It has a median age of onset of about 50 years. The incidence of CML is about 1-1.5 per 100,000 persons per annum.8 There appears to be no association with social class or ethnicity, and its incidence appears to be remarkably constant worldwide.9 Some reports suggest a slightly higher prevalence in some parts of India and China, in particular Hong Kong, but these remain unconfirmed.

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