Failure To Attain A Cr In Less Than 45 Weeks

Several clinical studies have identified the importance of time required to attain first remission as a significant prognostic factor in adult ALL.816

Table 13.1 Prognostic factors in

adult ALL identifying risk groups for treatment—

-stratification

Prognostic factor

Ref

Good risk

Standard risk

Poor risk

Clinical age Presenting WBC Time to CR

S, 6-16

<30 years <30,000/ul_ <2-4 weeks

30-60 years old <30,000/ul_ 2-4 weeks

60 years

>30,000/ul_ (precursor B) >2-4 weeks

Immunophenotype

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