I

'*• Palliative care if poor performance status

Consider clinical trial Consider allogeneic stem cell transplant

As long as CLL remains incurable, multiple new avenues of research will be explored for patients with CLL. Newer approaches target antigenic determinants,

(Consider clinical trial at all decision points)

Figure 26.1 Treatment approach to chronic lymphocytic leukemia escalation rather than by initiating therapy at 25 mg per day. Myelosuppression was also commonly experienced.

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