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PFS, progression-free survival; EFS, event-free survival; OS, overall survival; NR, not reported.

PFS, progression-free survival; EFS, event-free survival; OS, overall survival; NR, not reported.

lymphoblastic lymphoma 42.0%; Burkitt's lymphoma 37.1%; and Hodgkin's disease 24.7%. These outcomes are relatively poor because of the high procedure-related mortality associated with these procedures, particularly in patients with Hodgkin's disease (51.7% actuarial procedure-related mortality at 4 years). Multivariate analysis showed that for all lymphomas apart from Hodgkin's disease, status at transplantation significantly affected outcome. A matched analysis revealed that for all categories of lymphoma, overall survival was better for auto SCT than for allo SCT. Relapse rate was better in the allo SCT group for low-, intermediate- and high-grade, and lymphoblastic NHL. Allo SCT appeared superior to auto SCT in producing a lower relapse rate, but overall survival will not be superior until the toxicity of such procedures is reduced.

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