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aFrom one series only.11

aFrom one series only.11

factors shown to be independently significant on eventfree survival (with event being relapse or treatment failure) in pathological stage I-II patients treated with radiotherapy alone, clinical stage I-II patients treated with radiotherapy alone, clinical stage I-II patients treated with combined-modality therapy, in those treated with chemotherapy alone (in one series only),11 or in patients with advanced disease. Some of these factors have also proved to predict for laparotomy findings in supradi-aphragmatic clinical stage I-II patients. Beside age and gender always mentioned, the number of involved regions, mediastinal involvement (more often bulky) or tumor burden, histologic subtype, B symptoms, and ery-throcyte sedimentation rate are commonly reported over all settings. However, this data mostly concerns adult patients; very few are known in pediatric patients, thanks to the success obtained with combined-modality therapies since the late 70s.

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