Info

NLPHL, nodular lymphocyte-predominant Hodgkin lymphoma; MDS, myelodysplastic syndrome; AML, acute myelogenous leukemia.

NLPHL, nodular lymphocyte-predominant Hodgkin lymphoma; MDS, myelodysplastic syndrome; AML, acute myelogenous leukemia.

suggested a continuous pattern of relapse up to 10 years or more after diagnosis and treatment.29-31 Many patients had multiple relapses. One study suggested that patients with localized disease were less likely to relapse.31 Another found that relapses occurred more commonly outside the initial radiation field.32 In four of these series, subsequent NHL was documented in 0 of 71, 4 of 68, 6 of 219, and 1 of 42 patients.29-31'33 Despite the risk of relapse, the overall survival was extraordinarily good and ranged from 71 to 94% at 8-15 years. The HL-specific overall survival for the 219 NLPHL patients in the ETFL project is shown in Figure 74.1.29 In this series, survival was worse for patients with stage IV disease (i.e., 41% at 8 years). Of 95 deaths reported in four of these series, only 16 were attributable to HL; most of the remaining patients were in remission at the time of death.29-3133 Second malignancies and cardiovascular disease were the most common cause of death (Table 74.2).

Your Heart and Nutrition

Your Heart and Nutrition

Prevention is better than a cure. Learn how to cherish your heart by taking the necessary means to keep it pumping healthily and steadily through your life.

Get My Free Ebook


Post a comment