The previous chapters in this book have taken us through the epidemiology of acute myeloid leukemia (AML); its pathology and molecular biology; and the nuances of making the diagnosis, treatment options for both younger and older adults, and for special populations of AML patients [such as those with acute pro myelocytic leukemia (APL) and secondary AML]. This chapter will address the next step in the thought process about AML, defining remission, predicting which patients are more or less likely to enter a remission and enjoy long-term disease-free survival, and it will provide guidelines for following AML patients once they have achieved a remission.

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