John W Sweetenham

The development of the Revised European American Lymphoma Classification and the subsequent World Health Organization (WHO) Classification of tumors of the hematopoietic and lymphoid tissues has resulted in a departure from the traditional "grading" of non-Hodgkin's lymphomas (NHLs) intrinsic to older lymphoma classifications, particularly the Working Formulation.1 Despite this, the designation of high-grade NHL is generally considered to encompass Burkitt's lymphoma and precursor B-cell and T-cell lymphoblastic lymphoma/leukemia. Additionally, the entity of "atypical" Burkitt/Burkitt-like lymphoma, used to identify a group of aggressive B-cell NHLs with features in common with Burkitt's lymphoma (BL) and diffuse large B-cell NHL (DLBCL), is also included in this group of diseases.

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